This week, we finished working on surgeries for the cohort of our experimental mice. I’m glad I had the chance to do this: at this point I feel significantly more confident as a mouse surgeon than I did at the beginning of June. I also attended another lab meeting and got more context for one of the ongoing projects in the Liston lab. In addition to lab work, this week I got to see a clinical procedure. On Wednesday, I saw a MRI-guided focused ultrasound ablation. It was done in an Alzheimer’s patient to help stabilize tremors. It was remarkable to see just how significantly the patient’s control of motor function improved after. The precision is stunning too. I know that the brain region targeted in this procedure is adjacent to other important regions (e.g. speech-related), so the clinician has to be extra careful about not accidentally damaging those areas. Next week, I am looking forward to getting started on 2P imaging in the Liston lab, and hopefully getting to see some more clinical work.
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