For my summer immersion term, I am working with Dr. Bostrom at the Hospital for Special Surgery (HSS). This week was largely focused on developing my research project for the summer, which involves designing a 3D-printed structure to hold the hindlimbs of mice for Faxitron imaging. Currently, when the Bostrom lab images, there is an inherent error due to inconsistencies in mouse limb placement. This 3D-printed device will allow them to obtain a consistent limb angle and height for Faxitron image analysis purposes. Before beginning this, I completed lab safety training and had meetings with Bostrom lab members as well as Dr. Tony Chen to discuss the best approach for developing this structure. In order to properly size the implant, we will need to determine the average length of the mice's femurs and tibias. I observed a post-doc in the lab do tibia and femoral dissections and got the opportunity to try a couple of femur dissections myself. Other lab activities I had the chance to observe were H&E staining, which was used to evaluate bone growth through confocal imaging, and microCT analysis of tibial bones. The microCT was performed to determine bone volume in the area around a surgical implant. Lastly, I attended a couple of research talks, the first was focused on lung fibrosis, and the other was on custom implant development.
No comments:
Post a Comment